Ngokusebenzisa i-polyfunctionality ye-carbohydrates, i-acid catalyzed reactions ye-Fischer ihlelwa ukuba ivelise umxube we-oligomer apho i-avareji engaphezu kweyunithi ye-glycation idityaniswe kwi-microsphere yotywala.I-avareji yenani leeyunithi ze-glycose ezidityaniswe kwiqela le-alcohol lichazwa njenge-(avareji) ye-polymerization degree (DPI. Figure2 ibonisa ukuhanjiswa kwe-alkyl polyglycoside kunye ne-DP = 1.3.) Kulo mxube, ukuxinwa kwe-oligomers nganye (i-mono- ,di-,tri-,-,glycoside) ubukhulu becala ixhomekeke kumlinganiselo weglucose kwi-alcohol kumxube wokusabela.Umndilili weqondo lepolymerization(DP) luphawu olubalulekileyo ngokumalunga nekhemikhali yomzimba kunye nokusetyenziswa kwealkyl polyglycosides. Ekuhanjisweni okulinganayo, i-DP- yobude be-alkyl chain chain-correlates kakuhle kunye neempawu zemveliso ezisisiseko, ezifana ne-polarity, i-solubility, njl. Ngokomgaqo, oku kusasazwa kwe-oligomer kunokuchazwa ngu-PJFlory ngokuchaza ukuhanjiswa kwe-oligomer yeemveliso ezisekelwe ii-polyfunctional monomers zinokusetyenziswa kwi-alkyl polyglucosides Olu guqulelo lulungisiweyo losasazo lweFlory luchaza i-alkyl polyglycosides njengomxube we-oligomers ezisasazwe ngokweenkcukacha-manani.
Umxholo weentlobo zomntu ngamnye kumxube we-oligomer uyancipha ngokunyuka kweqondo le-polymerization.Ulwabiwo lwe-oligomer olufunyenwe ngulo mzekelo wemathematika luhambelana kakuhle neziphumo zohlalutyo (jonga iSahluko 3).Ngamagama alula, umyinge weqondo lepolymerization(DP) yealkyl polyglycoside imixube ingabalwa ukusuka kwimole yepesenti pi yeentlobo ze oligomeric ezifanelekileyo "i" kumxube weglycoside (Figure 2)